Application-wide settings live in the Settings (cogs) menu on the Project Browser. These apply to Lightworks as a whole, on this machine, for this user - as distinct from per-project settings (see Project settings reference).
The User Interface group covers how Lightworks looks and behaves:
Flexible layout has a second preferences panel of its own, opened from the settings button at the foot of the Toolbox. It covers the desktop rather than the application: tool positions, the Toolbox captions, the on-screen console, fast room switching, and the desktop wallpaper (see Panel and UI customisation).
The Hardware group configures physical devices:
The Settings menu also shows Information which includes a way to show the system logs, useful for support requests.
Clicking on the avatar icon in the top right of the Project Browser shows your account information.
Your licences type is also shown, you can manage licences by clicking on the Activate licenses button.
Preferences can be exported to a file and imported on another machine, so a carefully tuned setup - appearance, behaviour, shortcuts - can move between workstations.
Tip: After setting up a machine the way you like it, export your preferences and keep the file with your project archives. Rebuilding a workstation then takes minutes, not an afternoon.